(-)-3,3,3-Trifluoro-2-methyl-L-lactic acid - Names and Identifiers
Name | (2R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropanoic acid
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Synonyms | (-)-3,3,3-Trifluoro-2-methyl-L-lactic acid (R)-3,3,3-TRIFLUORO-2-HYDROXYISOBUTYRIC ACID (R)-2-(TRIFLUOROMETHYL)-2-HYDROXYPROPIONIC ACID (R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionic (R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionic acid (R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPIONIC ACID (R)-2-Hydroxy-2-methyl-3,3,3-trifluoropropanoic acid (R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropanoic acid (2R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropanoic acid (R)-(+)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPIONIC ACID Propanoic acid, 3,3,3-trifluoro-2-hydroxy-2-methyl-, (2R)-
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CAS | 44864-47-3
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InChI | InChI=1/C4H5F3O3/c1-3(10,2(8)9)4(5,6)7/h10H,1H3,(H,8,9)/t3-/m1/s1 |
(-)-3,3,3-Trifluoro-2-methyl-L-lactic acid - Physico-chemical Properties
Molecular Formula | C4H5F3O3
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Molar Mass | 158.08 |
Density | 1.532±0.06 g/cm3 (20 ºC 760 Torr) |
Melting Point | 110 °C |
Boling Point | 247.4±35.0℃ (760 Torr) |
Flash Point | 103.4±25.9℃ |
Water Solubility | Soluble in water |
Vapor Presure | 0.0042mmHg at 25°C |
Appearance | powder to crystal |
Color | White to Almost white |
pKa | 2.46±0.22(Predicted) |
Storage Condition | Inert atmosphere,2-8°C |
Refractive Index | 16.5 ° (C=5, H2O) |
MDL | MFCD03095400 |
(-)-3,3,3-Trifluoro-2-methyl-L-lactic acid - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 34 - Causes burns
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S24/25 - Avoid contact with skin and eyes.
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UN IDs | 3261 |
HS Code | 29155090 |
Hazard Class | IRRITANT |
Packing Group | III |
(-)-3,3,3-Trifluoro-2-methyl-L-lactic acid - Introduction
(R)-3,3, 3-Trifluoro-2-hydroxy-2-methylpropionic acid is an organic compound with the chemical formula C4H7F3O3.
Nature:
-Appearance: Colorless liquid or white solid.
-Melting point: about 50°C.
-Boiling point: about 200°C.
-Solubility: Soluble in water, alcohol and ether.
Use:
- (R)-3,3, 3-trifluoro-2-hydroxy-2-methylpropionic acid is often used as a chiral building block in drug synthesis, and can be used to synthesize chiral drugs and pesticides.
-It can also be used to synthesize regular optical molecules and potential materials applications.
Preparation Method:
- (R)-3,3, 3-trifluoro-2-hydroxy-2-methylpropionic acid can be synthesized by fluorination reaction.
-The specific synthesis method may be to react 2-methylmalonic acid with hydrofluoric acid under appropriate conditions to obtain (R)-3,3, 3-trifluoro-2-hydroxy-2-methylpropionic acid.
Safety Information:
- (R)-3,3, 3-trifluoro-2-hydroxy-2-methylpropionic acid is an organic acid, which is relatively stable and generally does not have serious toxicity and irritation.
-During use and handling, direct contact with skin and eyes should be avoided, inhalation or intake should be avoided, and good ventilation conditions should be maintained.
-Wear appropriate personal protective equipment such as goggles, gloves and protective clothing during use.
-When handling waste, it should be handled and disposed in accordance with relevant laws and regulations.
Last Update:2024-04-09 02:00:46